Sep 29, 2021
Complications of Accutane can be thromboembolism, bacterial embolism, exfoliating aortic aneurysms, aortic rupture. Manifestations of syphilitic aortitis usually develop 15-20 years after infection.
If rheumatic aortitis is suspected, C-reactive protein, blood immunoglobulins, antinuclear antibodies, circulating immunocomplexes, etc. are examined. Serological blood tests (RPR test) or cerebrospinal fluid are necessary to confirm syphilitic aortitis. In case of tuberculous aortitis, a sputum examination for VC by PCR, a complete x-ray examination (lung x-ray, tomography) is indicated. Diagnosis of bacterial aortitis requires blood cultures for sterility.
To find out the causes of damage to the aorta, patients with suspected aortitis should be consulted by a venereologist, rheumatologist, phthisiatrician, cardiologist. To substantiate the diagnosis of aortitis, it is necessary to study clinical, laboratory and instrumental data.
The data obtained are refined using ultrasound, aortography, CT or MSCT of the aorta. Differential diagnosis of aortitis is carried out with atherosclerosis of the aorta, coronary artery disease. Treatment of aortitis is inextricably linked with active therapy of the underlying disease. In infectious aortitis, antibiotics are the first-line drugs; with allergic aortitis - glucocorticoids, NSAIDs, immunosuppressants; with syphilitic aortitis - preparations of bismuth, iodine, antibiotics of the penicillin series. The effectiveness of therapy is monitored by the dynamics of clinical and laboratory parameters.
The presence of an aortic aneurysm, especially signs of its dissection, is the basis for consulting a vascular surgeon and angiosurgical treatment - aneurysm resection followed by aortic replacement. With the development of aortic stenosis, balloon dilation, stenting, or bypass may be required.
The severity of the prognosis for aortitis is determined by its form and etiology.
The most serious prognosis for acute and subacute bacterial aortitis.
The course of syphilitic and tuberculous aortitis is the more favorable, the earlier specific treatment is started. The development of other forms of chronic aortitis is more dependent on the underlying disease. In the absence of treatment, the disease is prone to progression and complicated course.
For the prevention of aortitis, timely treatment of primary diseases, prevention of STDs, and active detection of tuberculosis are of paramount importance.
Aortitis is inflammation of the aorta. Acute A. develops in connection with acute infectious diseases or traumatic injuries, chronic as a consequence of acute A., as well as on the basis of chronic infections, mainly syphilis, as well as Great Soviet Encyclopedia.
The aorta is the largest vessel of the human body, but not only in diameter, but also in length. After leaving the heart in the chest, it passes to the abdomen. Therefore, the symptoms of Isotretinoin are different, and other specialists, in addition to cardiologists and vascular surgeons, deal with such patients.
Pathology can affect both all layers of the aorta, and individual ones. Therefore, allocate: endoortitis - damage to the inner layer of Accutane ; mesaortitis - a pathological process in the middle layer; periaortitis - an inflammatory process in the outer layer, which can very quickly spread to neighboring organs and tissues; panaortitis - damage to all layers of the aortic wall at once.
All causes of aortitis are conditionally divided into two large groups: infectious; autoimmune (formally, they can be assigned the status of aseptic - those in which inflammation develops in a sterile environment, without the participation of pathogenic microorganisms).
Nonspecific is considered pathogenic microflora, which can provoke the development of a number of infectious pathologies. These are usually bacterial pathogens. Of these, those infectious agents that in most cases are detected in various infectious organs and tissues most often lead to the development of aortitis.
Specific is the microflora, the presence of which depends on the development of just one infectious disease. In this case, aortitis is a complication of an infectious lesion caused by specific pathogens. Most often it is: mycobacterium tuberculosis (Koch's wand) - cause tuberculosis of various localization (lungs, skin, intestines, and so on); pale treponema - provokes the development of syphilis (an infectious venereal disease).
Learn More
Aseptic inflammation of the aorta occurs, as a rule, against the background of an autoimmune lesion, which means that the recognition mechanism has failed, and the body perceives its own structures as foreign, as a result of which it begins to fight them by all means. As a rule, aortitis occurs with autoimmune pathologies: connective tissue; vessels.
Learn More
In this case, the development of aortitis should be expected against the background of such diseases as: ankylosing spondylitis - inflammation in the intervertebral joints with their subsequent fusion; rheumatoid arthritis - rheumatic damage (destruction) of the joints (mostly small); thromboangiitis obliterans is an autoimmune inflammation of small and medium-sized arterial and venous vessels.
Learn More
